Thyroid glands are known to produce two typical hormones, triiodothyronine (T3) and thyroxine (T4). They are plainly responsible for certain metabolic procedures like regulating temperature, weight, growth, heart rate, development, etc. In fact, these hormones are produced from a unique combination of the amino acid tyrosine and iodine.
You should clearly understand that Liothyronine and Levothyroxine are particularly synthetic versions of T3 and T4, respectively. Today, this article will give you valuable insights into the two research liquids. Click here to know more about these. And while you dig further, you will get to know its effects and functionalities.
Liothyronine (T3) – What is it?
T3 is nothing but a synthetic research liquid of the otherwise naturally occurring thyroid hormone. It typically helps in binding to the nuclear thyroid receptors, thereby inducing gene expression. This is actually crucial for both growth and development. You should also note that Liothyronine is extremely potent in comparison to Levothyroxine.
Mechanism of Action for Liothyronine (T3)
Liothyronine efficiently replaces the otherwise endogenous thyroid hormone. Further, it controls DNA transcription and protein synthesis, thereby exerting its physiological effects. This effect deliberately occurs whenever it binds to all h thyroid receptors, typically attached to the DNA.
Further, it efficiently increases energy expenditure, thereby stimulating the maturation, growth, and metabolism of the body tissues. It also helps in the development of synaptic processes and myelination of nerves. All these happen within the nervous system, enhancing carbohydrate and protein metabolism.
Levothyroxine (T4) – What is it?
Levothyroxine is also a synthetic version of thyroxine or T4, another natural thyroid hormone. It is typically administered when there is a deficiency of thyroxine within the body. This useful liquid helps in treating stringent myxedema coma or hypothyroidism in the test subjects.
Further, it demonstrates magnificent beneficial effects in thyroid cancer and euthyroid goiters in animals that underwent thyroidectomy. On the other hand, it typically serves as an adjunct to both radioiodine therapy and surgery.
Mechanism of Action for Levothyroxine (T4)
You should know that the thyroid receptor protein is bound within the nucleus by T4. Further, it is typically converted to its active metabolite, L-triiodothyronine, thereby controlling DNA transcription and protein synthesis. It’s also worth mentioning that Levothyroxine is a typical chiral compound in the L-form.
Research on test subjects suggests that T4 is smoothly absorbed from the gastrointestinal tract. Nevertheless, pacific malabsorption syndromes’ absorption capacity is decreased and improved by fasting.
Why is Levothyroxine Preferred Over Liothyronine?
By now, you will probably know that both research liquids are synthetic versions of T3 and T4. Most importantly, both are used for treating hypothyroidism. Nevertheless, researches prove that Levothyroxine is the most preferred liquid over liothyronine.
This is primarily because the latter is absorbed from the intestine very rapidly. Thus, it might significantly result in mild thyroid hormone toxicity.
Before you can purchase these research liquids from Loti Labs, there are a few things that you should know. The life of Levothyroxine typically ranges from 6-7 days, while that of liothyronine ranges between 1-2 days. Nevertheless, these liquids are deemed to undergo various other trials for detecting further usage.